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呼吸窘迫综合征(RDS)是新生儿死亡的一大原因。辅助呼吸对伴有肺部疾患的早产儿有明显疗效,可是需要辅助呼吸的婴儿中发病率高,约有24%肺部漏气,20%肺支气管发育不良。虽然急慢性肺损伤的确切病生理机制尚不清楚,可以想像高压通氧和因而产生的压力性损伤是造成肺损伤的重要因素。因为高频给氧与普通频率相比可以在较低的气道压下进行充分气体交换,故高频给氧也可以用于抢救已发生肺气压伤或普通给氧失败的婴儿。早期应用高频给氧,可以预防气压伤的发生,现在高频射流通气(HFJV)已广泛应用于临床。为了对高频的流通气(HFJV)与限压循环或常规通气(CV)治疗作对
Respiratory distress syndrome (RDS) is a major cause of neonatal death. Auxiliary breathing has a significant effect on premature infants with pulmonary conditions, but the incidence of infants with assisted breathing is high, with about 24% of lungs and 20% of lungs with bronchopulmonary dysplasia. Although the exact pathogenesis of acute and chronic lung injury is not yet known, it is conceivable that hyperbaric oxygenation and consequent stress injuries are important contributors to lung injury. Because high-frequency oxygen provides ample gas exchange at lower airway pressures than normal, high-frequency oxygenation can also be used to rescue infants who have had a barotrauma or a general failure to deliver oxygen. Early application of high-frequency oxygen, can prevent the occurrence of barotrauma, and now high-frequency jet ventilation (HFJV) has been widely used in clinical. In order to respond to high-frequency ventilation (HFJV) with pressure-limiting or conventional ventilation (CV)