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目的观察氯沙坦钾联合至灵胶囊治疗早期糖尿病肾病的疗效。方法选取2014年6月-2015年1月期间中心收治的早期糖尿病肾病患者100例,随机分为两组各50例。对照组单独应用氯沙坦钾,观察组联合应用氯沙坦钾与至灵胶囊。观察两组患者治疗前后24 h尿微量清蛋白、肌酐及尿素氮改善情况。结果观察组在24h尿微量清蛋白、肌酐及尿素氮较对照组存在差异并且总有效率高于对照组,差异有统计学意义(P<0.05)。结论氯沙坦钾联合至灵胶囊治疗早期糖尿病肾病疗效确切。
Objective To observe the effect of losartan potassium combined with lingzhi capsule on early diabetic nephropathy. Methods One hundred patients with early diabetic nephropathy admitted from June 2014 to January 2015 were randomly divided into two groups of 50 cases each. Control group losartan potassium alone, the observation group combined losartan potassium and Zhiling capsule. The changes of urinary albumin, creatinine and urea nitrogen 24 hours after treatment in both groups were observed. Results Urine microalbuminuria, creatinine and urea nitrogen in the observation group were significantly different from those in the control group at 24 hours and the total effective rate was higher than that of the control group (P <0.05). Conclusion Losartan combined with Zhuling Capsule in the treatment of early diabetic nephropathy is effective.