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目的观察甘草酸二铵注射液治疗慢性乙型肝炎的疗效分析。方法患者应用甘草酸二铵注射液150 mg 1次/d静滴,疗程24 d,并且监测治疗前后肝功能的指标(ALT、AST)、黄疸的指标(TBUL),运用t配对检验进行分析。结果60名慢性乙型肝炎患者应用甘利欣注射液治疗总有效率为91.67%(显效36例,占60.00%,有效19例,占31.67%),治疗前ALT、AST、TBULB分别为(445.49±417.52)、(248.56±226.95)、(26.41±24.70),治疗后分别为(71.43±69.09)、(50.69±59.97)、(14.28±6.25),2者比较有显著性意义,P<0.01。结论甘草酸二铵注射液治疗慢性乙型肝炎,可明显改善患者症状、体征,降酶、退黄、促使肝细胞修复作用效果明显。
Objective To observe the efficacy of diammonium glycyrrhizinate injection in the treatment of chronic hepatitis B. Methods Patients were treated with diammonium glycyrrhizinate 150 mg once daily for 24 days. The indexes of liver function (ALT, AST) and jaundice (TBUL) before and after treatment were monitored and analyzed by t-paired test. Results The total effective rate of 60 patients with chronic hepatitis B treated with salvia miltiorrhiza injection was 91.67% (effective in 36 cases, 60.00%, effective in 19 cases, accounting for 31.67%). Before treatment, ALT, AST and TBULB were (445.49 ± 417.52), (248.56 ± 226.95) and (26.41 ± 24.70), respectively, after treatment were (71.43 ± 69.09) and (50.69 ± 59.97) and (14.28 ± 6.25) respectively. There was significant difference between the two groups (P <0.01). Conclusion Glycyrrhizic acid diammonium injection for the treatment of chronic hepatitis B can significantly improve the symptoms, signs, reducing enzymes, reversion, promote liver cell repair effect is obvious.