Angew.Chem.Int.Ed.2017,56,5817~5820吡啶的还原反应是有机合成研究中非常重要的课题,其还原产物哌啶或者四氢吡啶等含氮杂环是许多药物及生物活性分子的构成片段.过渡金属催化是工业中最常用的吡啶还原方法,然而,这些方法多使用贵金属,经济性和官能团兼容性都不够理想.近期,南开大学化学学院王晓晨课题组使用B(C_6F_5)_3作为催化剂,二苯基硅烷(或频哪醇 Angew.Chem.Int.Ed.2017,56,5817-5820 The reduction reaction of pyridine is a very important subject in the field of organic synthesis. Nitrogen-containing heterocycles, such as piperidine or tetrahydropyridine, are the reductive products of many drugs and bioactive molecules Transition metal catalyst is the most commonly used in industry pyridine reduction method, however, these methods use more precious metals, economic and functional group compatibility are not ideal .Recently, Nankai University School of Chemistry Wang Xiaochen use B (C_6F_5) _3 As a catalyst, diphenylsilane (or pinacol