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原发于甲状腺的恶性淋巴瘤十分罕见,本文收集3例,报告于下。例1:女,37岁。发现右颈前一蚕豆大肿块2个月,近月来明显增大,无自觉不适。体查:一般情况好,右侧甲状腺可扪及4cm×4cm肿块,质较硬,表面光滑,随吞咽活动;颈部及全身浅淋巴结不肿大。~(131)Ⅰ扫描示右甲状腺冷结节,T_3,T_4正常,血常规正常。以甲状腺腺瘤行右侧甲状腺次全切除术。病理检查:甲状腺下极有一4cm×3cm×2cm肿块,有包膜,切面灰红均匀;镜检见瘤细胞弥漫分布,细胞中等大,由裂细胞及无裂细胞构成;甲状腺滤泡破坏,滤泡内及周围有弥漫的瘤细胞浸润。病理诊断:右甲状腺原发性非何杰金恶性淋巴瘤(裂-无裂混合型)。
Malignant lymphomas that are primary in the thyroid gland are rare. This article was collected in 3 cases and reported below. Example 1: Female, 37 years old. A large mass of broad bean in front of the right neck was found for 2 months. It has obviously increased in recent months without any conscious discomfort. Physical examination: In general, the right side of the thyroid can be paralyzed and 4cm × 4cm mass, hard, smooth surface, with swallowing activities; neck and general superficial lymph nodes are not swollen. A ~(131)I scan showed a right thyroid cold nodule with normal T_3, T_4, and normal blood routine. Right thyroid subtotal resection was performed with thyroid adenoma. Pathological examination: The inferior pole of the thyroid gland has a 4cm × 3cm × 2cm mass, enveloped, and the cut surface is gray and red; the tumor cells are diffusely distributed and the cells are medium in size, composed of split cells and non-cleaved cells; thyroid follicle destruction, filtration Diffuse tumor cells infiltrate into and around the bubble. Pathological diagnosis: Primary thyroid primary non-Hodgkin’s malignant lymphoma (split-no-crack mixed type).