喉癌是喉部最常见的恶性肿瘤,其发病率目前有明显增长趋势,其中东北地区发病率最高,占全身恶性肿瘤的5.7%~7.6%〔1〕。目前国内外关于β-catenin与喉癌发生、发展关系的研究不多,本实验采用免疫组织化学法检测喉癌组织中β-catenin的表达情况,探讨β-catenin蛋白在喉癌发生、发 Laryngeal cancer is the most common malignant tumor in the larynx. The incidence of laryngeal cancer is obviously increasing at present. The incidence rate of the disease in Northeast China is the highest, accounting for 5.7% to 7.6% of the total body malignant tumors (1). At present, there are not many studies on the relationship between β-catenin and laryngeal carcinoma in our country. In this study, the expression of β-catenin in laryngeal carcinoma was detected by immunohistochemistry,