目的 :为探索治疗巨人症或肢端肥大症的药物 ,我们观察了党参对兔的下丘脑和大脑皮质中生长抑素的作用。方法 :将白兔 40只分别灌喂党参煎剂或蒸馏水 ,1个月后用放免法测定下丘脑和大脑皮质中生长抑素的浓度。结果 :党参对兔的下丘脑、大脑皮质中的生长抑素无任何影响 ,P >0 .0 5。结论 :提示党参对巨人症或肢端肥大症的生长激素过多分泌可能无作用 Objective: To explore the drugs for the treatment of giant or acromegaly, we observed the effects of Dangshen on somatostatin in the hypothalamus and cerebral cortex of rabbits. Methods: 40 rabbits were fed with Dangshen decoction or distilled water respectively. After 1 month, the concentrations of somatostatin in the hypothalamus and cerebral cortex were measured by radioimmunoassay. Results : Codonopsis pilosula had no effect on somatostatin in the hypothalamus and cerebral cortex of rabbits, P > 0.05. Conclusion : It is suggested that Dangshen may not have effect on excessive secretion of growth hormone in giant or acromegaly