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An alternative route for the synthesis of (-)-10-epi-α-cyperone 1 starting from (+)- dihydrocarvone 2 is described by using an asymmetric Michael addition as a key step. The route features more efficiently and can be performed in large scale.
An alternative route for the synthesis of (-) - 10-epi-α-cyperone 1 starting from (+) - dihydrocarvone 2 is described by using an asymmetric Michael addition as a key step. The route features more efficiently and can be performed in large scale