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目的探讨高血压患者Ig、C3以及CD3、CD4和CD8水平与左心室肥厚的相关性。方法选取2009年12月-2010年1月的80例高血压患者为研究对象,将其分为A组(伴左心室肥厚组)40例和B组(不伴左心室肥厚组)40例,同时选取40名健康人为C组,后将三组人员的Ig、C3以及CD3、CD4和CD8水平进行研究及比较。结果 A组的Ig、C3及CD8均高于B组及C组,CD3、CD4则低于B组及C组,差异均有统计学意义(P均<0.05)。结论高血压伴左心室肥厚患者的Ig、C3以及CD3、CD4和CD8水平变化较大可为其是否伴有左心室肥厚的判断提供一定的依据。
Objective To investigate the correlation between the levels of Ig, C3, CD3, CD4 and CD8 in patients with hypertension and left ventricular hypertrophy. Methods Eighty hypertensive patients from December 2009 to January 2010 were selected and divided into 40 cases in group A (with left ventricular hypertrophy) and 40 cases in group B (without left ventricular hypertrophy) At the same time, 40 healthy individuals were selected as group C. The levels of Ig, C3, CD3, CD4 and CD8 in three groups were studied and compared. Results The Ig, C3 and CD8 in group A were higher than those in group B and C, while the levels of CD3 and CD4 in group A were lower than those in group B and C (all P <0.05). Conclusion The changes of Ig, C3, CD3, CD4 and CD8 in hypertensive patients with left ventricular hypertrophy may provide a basis for judging whether they are associated with left ventricular hypertrophy.