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1978年7月,日本长野县爆发了一起推测为进食生鱼片所引起的集体腹泻疾病,在援食的135人中有18人发病,发病率为13.3%。疾病的潜伏期从4.5到13小时,平均8.5小时。临床表现为似霍乱样腹泻的急性胃肠炎症状,主要特征是腹痛、水样腹泻(1～6次)和发烧(37.1～37.8℃),约半数患者有呕吐(1～5次)和寒战。12人曾住院治疗。检查9个患者的粪便标本,其中8个检出了霍乱弧菌。进一步对有关食品进行检查,于生鱼片和烤鸡肉中分离出本菌。根据对做菜情况的考察,推测烤鸡肉是受生鱼片的污染,认为生鱼片是这次发病的传染源。从上述8名患者和2种食品检出的10株
In July 1978, a collective diarrhea erupted in Nagano prefecture, Japan, presumed to have eaten sashimi. An incidence of 13.3% of the 135 people who were eaten were eighteen. The incubation period for the disease ranged from 4.5 to 13 hours, an average of 8.5 hours. Clinical manifestations are cholera-like diarrhea-like signs of acute gastroenteritis characterized by abdominal pain, watery diarrhea (1 to 6) and fever (37.1 to 37.8 ° C), vomiting (1 to 5) and shivering in about half of patients . 12 people have been hospitalized. Stool specimens from 9 patients were examined, of which 8 were V. cholerae. Further inspection of the food concerned was carried out to isolate the bacterium from sashimi and grilled chicken meat. According to the investigation of the cooking situation, speculated that roasted chicken is contaminated with sashimi, sashimi is considered the source of infection. Ten strains were detected from the eight patients mentioned above and two kinds of foods