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人类粒细胞抗原 (humanneutrophilantigen ,HNA)在临床上主要与输血相关性肺损伤 (TRALI)、发热性输血反应、新生儿同种免疫性粒细胞减少症等相关。目前已发现并命名的有 5个系统[1] 。HNA 1位于FcγRⅢb上 ,是目前发现的唯一具有多态性
Human granulocyte antigen (HNA) is clinically associated with transfusion-associated lung injury (TRALI), febrile transfusion reaction, and neonatal alloimmune neutropenia. There are currently five systems that have been discovered and named [1]. HNA 1 is located on FcγRIIIb and is the only polymorphism found so far.