目的:探讨神经内镜Endoport技术在累及室间孔的颅内病变切除术中的应用价值。方法:回顾性分析遵义医科大学附属医院神经外科自2018年1月至2020年8月采用神经内镜Endoport技术治疗的21例累及室间孔的颅内病变患者的手术效果及预后随访情况。结果:21例患者中，19例的病变全切除，2例次全切除；围手术期发生术后出血1例、颅内感染1例。随访3~30个月，除1例失访外，余20例患者术前出现过的神经功能障碍表现均有不同程度地改善[末次随访时Karnofsky功能状态评分为(85.5±3.5)分]，影像学随访均未发现病变复发迹象。结论:神经内镜Endoport技术能安全、有效地切除累及室间孔的颅内病变，患者预后良好。“,”Objective:To explore the application value of neuroendoscopic Endoport technique in resection of intracranial lesions involving the interventricular foramen.Methods:A retrospective analysis was performed; 21 patients with intracranial lesions involving the interventricular foramina accepted treatment by neuroendoscopic Endoport technique in our hospital from January 2018 to August 2020 were chosen. The surgical results and prognoses at follow-up were discussed.Results:In these 21 patients, total removal of the lesions was achieved in 19 patients, and subtotal removal in 2 patients; perioperative complications included 1 patient with postoperative hemorrhage and 1 patient with intracranial infection. During the follow-up of 3-30 months, except for 1 patient lost of follow-up, Karnofsky performance scale scores at the last follow-up were 85.5±3.5, and no signs of tumor recurrence were found during the imaging follow-up.Conclusion:Neuroendoscopic Endoport technique can help to safely and effectively remove intracranial lesions involving the interventricular foramen, and the patients enjoy good prognosis.