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通过本移植中心肾移植病人发生糖尿病病例的临床研究,发现肾移植后糖尿病的发病率为1.24%,好发于年龄较大、血环孢素A(CsA)浓度较高、肝功能有异常及有糖尿病家族史的受者,其发生与CsA的应用有密切关系。临床表现与一般糖尿病相类似,但感染发生率较高(90%),治疗方法除常规应用胰岛素、降糖药外,应首先停用或减少CsA的用量,并积极治疗感染,疗效尚可,治愈率为70%。
The clinical study of diabetic patients with renal transplant recipients in this transplant center found that the incidence of diabetes after kidney transplantation was 1.24%, which occurred in older patients with higher concentration of CsA and liver function Abnormal and have a family history of diabetes, its occurrence is closely related to the application of CsA. Clinical manifestations and general diabetes are similar, but the incidence of infection is high (90%), in addition to the conventional treatment of insulin, hypoglycemic agents, you should first disable or reduce the amount of CsA and active treatment of infection, the effect is acceptable, The cure rate is 70%.