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Manuel 和他的同事报道了他们如何评估三种针对加拿大人群的降脂策略的有效性(见本期第25,44页)。其中“全人群”策略设想使整个人群的血胆固醇水平下降2%,冠心病死亡下降2.7%。另外两个策略是以患者为基础的,设想通过给冠心病高危患者服用他汀类药物可以使这些人的危险下降27%。“单一危险因素”策略是针对血胆固醇水平
Manuel and colleagues reported how they assessed the effectiveness of three lipid-lowering strategies for the Canadian population (see pages 25 and 44 of this issue). The “whole population” strategy envisions a 2% reduction in blood cholesterol levels and a 2.7% decrease in coronary heart disease deaths. The other two strategies are patient-based and envisage a 27% reduction in the risk of these people by taking statins at high risk of coronary heart disease. The “single risk factor” strategy targets blood cholesterol levels