以腰骶神经根痛为主要表现的多发性骨髓瘤较少见 ,现报告 1例如下。1　病例　男 ,46岁。因发作性腰骶部剧痛 2个月于 1 998年1 0月 1 7日入院。患者 2个月前开始出现腰骶部剧痛 ,向双下肢放散 ,左下肢为著 ,咳嗽及用力时加剧 ,午后及夜间更甚 ,每次持续约 1 0小时 ,均需肌注度 To lumbosacral nerve root pain as the main manifestation of multiple myeloma is rare, is reported in 1 case as follows. 1 case male, 46 years old. Due to the onset of lumbosacral pain for 2 months in January 1998 January 17 admission. Patients began to appear lumbosacral pain 2 months ago, to the lower extremity excretion, left lower extremity as the cough and forced to intensify in the afternoon and even more, each lasting about 10 hours, are required intramuscular injection