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目的:探讨老年糖尿病高血压合并高尿酸血症患者采用厄贝沙坦联合苯磺酸氯地平治疗的临床效果。方法:70例老年糖尿病高血压合并高尿酸血症患者随机分为两组,对照组35例给予厄贝沙坦治疗,观察组35例给予厄贝沙坦联合苯磺酸氯地平治疗。结果:治疗前两组血压和血尿酸水平无显著差异(P>0.05)。治疗后两组舒张压、收缩压和血尿酸等指标较治疗前均有改善,观察组各项指标下降水平较对照组更为明显(P<0.05)。结论:苯磺酸氯地平与厄贝沙坦联合用药在治疗老年糖尿病高血压合并高尿酸血症方面疗效确切,患者临床症状缓解明显,可在临床中推广应用。
Objective: To investigate the clinical effect of irbesartan combined with chlorpheniram besilate in elderly patients with hypertension and hyperuricemia. Methods: Seventy elderly hypertensive patients with hyperuricemia were randomly divided into two groups. 35 cases in the control group were given irbesartan and 35 cases in the observation group were treated with irbesartan and chlorpheniramine besylate. Results: Before treatment, there was no significant difference in blood pressure and serum uric acid between the two groups (P> 0.05). After treatment, the indexes of diastolic blood pressure, systolic blood pressure and serum uric acid in both groups were improved than those before treatment, and the decrease of each index in the observation group was more obvious than that in the control group (P <0.05). Conclusion: The combination therapy of beclodipine besilate and irbesartan is effective in the treatment of senile diabetic hypertension complicated with hyperuricemia. The patients’ clinical symptoms are relieved obviously and can be widely used in clinical practice.