读《新医学》1984年第7期“乙胺碘呋酮引起死亡4例报告”一文,有较大启发,使我今后在临床应用时加倍小心。但有如下问题提出商榷。1.关于乙胺碘呋酮口服作用时间,钟氏报告4～14天(平均7天),武汉报告其副反应出现于服药后4～49天(中位数14天),并未见严重的心血管毒性反应。而本组除第4例外,其余3例均在较短的时间出现严重的心血管毒性反应,这与文献的差异 Read the “New Medicine” 1984 the seventh period of “amiodarone-induced death in 4 cases” a report, a greater inspiration, so that I will be more careful in clinical applications. However, the following questions are open to question. 1. On oral administration of amiodarone, Chung reported 4 to 14 days (average 7 days). Wuhan reported that side effects occurred 4 to 49 days after treatment (median 14 days), with no serious findings Cardiovascular toxicity. The group in addition to the first four cases, the remaining three cases in a relatively short period of time serious cardiovascular toxicity, which is different from the literature