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8月10日,四川省医学科学院·四川省人民医院与重庆医科大学合作在《nature genetics》(SCI影响因子29.6)上发表文章,揭示了伏格特小柳原田综合征(Vogt-Koyanagi-Harada syndrome,VKH)的新增风险位点。VKH综合征是一种累及眼部、听觉系统、脑膜和皮肤的自身免疫性疾病,在有色人种中发病率高,其病因及发病机制尚不清楚。以往有研究从基因水平证实日本VKH患者主要与HLA-DRB1*0405密
On August 10, Sichuan Provincial Academy of Medical Sciences, Sichuan Provincial People’s Hospital and Chongqing Medical University published an article in “nature genetics” (SCI Impact Factor 29.6), revealing the Vogt-Koyanagi-Harada syndrome , VKH) the new risk sites. VKH syndrome is an autoimmune disease involving the eyes, auditory system, meninges and skin. The incidence of VKH is high in non-ferrous species. The etiology and pathogenesis of VKH syndrome are not yet clear. Previous studies have confirmed from the gene level in Japan VKH patients with HLA-DRB1 * 0405 close