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目的了解广西艾滋病感染者/患者接受抗病毒治疗及时性的现状,并分析其晚治疗的影响因素,为制定针对性的干预措施、提高治疗及时性提供科学依据。方法于2015年1月查阅国家艾滋病综合防治数据信息系统中的历史数据库,包括疫情库、随访库和抗病毒治疗库。用身份证号码将3个数据库进行链接,并对相关数据进行统计分析。结果广西2014年新入组治疗的成年艾滋病病毒感染者/患者9 381例,疫情库和随访库中能找到信息者8 150例,晚治疗比例为53.18%。因晚发现导致的晚治疗为3 414例,占78.77%,去除晚发现者,新入组治疗成年艾滋病病毒感染者/患者4 736例。单因素分析结果显示,性别、年龄、婚姻、文化程度、职业、感染途径、随访频率及接受首次CD4检测时限的晚治疗率有统计学差异(P<0.05)。多因素Logistic回归分析结果显示,年龄、婚姻、随访频率、接受首次CD4检测时限都是晚治疗的影响因素(P<0.05)。年龄≥60岁者及未婚者晚治疗危险性高,随访≥3次者晚治疗危险性降低,首次CD4检测时限延长,晚治疗危险性越大。结论晚发现、接受随访管理频率低、接受首次CD4检测晚、未婚、高年龄等均是晚治疗的影响因素,应加大艾滋病健康教育、检测发现、随访管理、CD4检测及心理疏导力度,提高艾滋病感染者/患者接受抗病毒治疗的及时性及依从性。
Objective To understand the status of timely treatment of antiviral therapy in HIV / AIDS patients in Guangxi and to analyze the influencing factors of late treatment, so as to provide scientific basis for making targeted interventions and improving the timeliness of treatment. Methods In January 2015, access to the historical database of the national AIDS integrated prevention and control data information system, including the outbreak database, follow-up database and anti-virus treatment database. With the ID number will be linked to three databases, and statistical analysis of the relevant data. Results A total of 9 381 adult HIV-infected patients / patients were enrolled in Guangxi in 2014. There were 8 150 informants in the outbreak and follow-up databases, and 53.18% in late treatment. 3 414 cases (78.77%) were late treatment due to late detection, 4 736 cases were newly treated to treat HIV / AIDS patients. Univariate analysis showed that gender, age, marital status, education level, occupation, route of infection, frequency of follow-up and late treatment rate of receiving the first CD4 test had statistical significance (P <0.05). Multivariate Logistic regression analysis showed that age, marital status, frequency of follow-up, and the time to first CD4 test were the influencing factors of late treatment (P <0.05). Patients aged ≥ 60 years and unmarried persons with high risk of late treatment, follow-up ≥ 3 times late treatment risk reduction, the first CD4 test extended the delay, the greater the risk of late treatment. CONCLUSIONS: It is found that the frequency of follow-up and follow-up management is low, and the first, late, unmarried, high-age patients receiving CD4 test are the influencing factors of late treatment. AIDS health education, detection and detection, follow-up management, CD4 testing and psychological counseling should be strengthened HIV / AIDS patients receive timely and compliant anti-virus treatment.