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目的对山东省１９８０年以来改水降氟工程进行调查，并对这些工程的经济投入和产出进行分析比较。方法随机抽取１０７处工程，用质量调整生命年（ＱＡＬＹＳ）为改水的产出指标，分析工程的效用及效用比。结果发现打井工程和骨炭除氟工程总成本无差异，人均成本后者大于前者，而产出的ＱＡＬＹＳ前者为１０年，后者为５．２６年，前者几乎为后者的２倍。其成本效用比（ＣＵＲ）显示打井工程优于骨炭除氟，在重病区改水的ＣＵＲ最小，即效用最大。结论改水使病区氟中毒病人生存质量改善，也促进了经济发展。
Objective To investigate the water and fluoride reduction projects in Shandong Province since 1980, and to analyze and compare the economic input and output of these projects. Methods A total of 107 projects were randomly selected, and QALYS was used as the output index to change water quality. The utility and utility ratio of the project were analyzed. The results showed that there was no difference in the total cost of drilling engineering and bone decontamination. The per capita cost was greater than the former while the former was 10 years and the latter was 5.26 years. The former was almost twice as much as the latter. The cost-utility ratio (CUR) shows that the well drilling project is superior to bone charcoal in removing fluoride, and the CUR is the least, ie, the most effective, for water diversion in seriously ill patients. Conclusion The improvement of water quality improves the quality of life of fluorosis patients in ward and promotes economic development.