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体外培养Wistar系乳鼠肝细胞,分为正常组、实验组和药物对照组,后两组分别加入草苁蓉和人参总皂甙.结果表明,实验组肝细胞脂褐素颗粒随着日龄的增加而明显减少,超氧化物歧化酶活性增强,过氧化脂质产物丙二醛含量降低,尤其是细胞培养的第14d和第21d,与正常组相比较均具有显著性差异(P<0.01),与药物对照组相比无显著差异.提示草苁蓉具有与人参相似的药理作用,可以做为抗衰老药物而开发应用.
Wistar rat hepatocytes were cultured in vitro and divided into normal group, experimental group, and drug control group. The latter two groups were added with Cistanche and ginsenoside respectively. The results showed that the lipofuscin granules in the liver of the experimental group decreased significantly with the increase of the age, the activity of superoxide dismutase increased, and the content of MDA of peroxidation lipid product decreased, especially on the 14th and 21st of cell culture. Compared with the normal group, there was a significant difference (P<0.01), and there was no significant difference compared with the drug control group. It is suggested that the herb has similar pharmacological effects to ginseng and can be used as an anti-aging drug.