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报道４５例慢性粒细胞白血病的骨髓细胞染色体检查结果．检出Ｐｈ１染色体阳性患者４２例，其中标准型Ｐｈ１染色体畸变３７例，标准型Ｐｈ１伴其它染色体易位者２例；双Ｐｈ１染色体者１例，变异Ｐｈ１染色体２例；还检出Ｐｈ１染色体阴性患者３例，其中２例为其它染色体畸变类型．结论：Ｐｈ１染色体是慢性粒细胞白血病的独立的细胞遗传学标志，双Ｐｈ１及标准型Ｐｈ１之外的染色体畸变可能预示着进入急变期，但变异Ｐｈ１染色体并不加快慢性期向急变期的转变．
Reported 45 cases of chronic myeloid leukemia bone marrow cell chromosome test results. 42 Ph1 chromosome positive patients were detected, including 37 Ph1 standard chromosome aberrations, 2 standard Ph1 with other chromosome translocations, 1 Ph chromosome with 1 Ph1 chromosome, and 2 Ph1 chromosomes; Ph1 chromosome negative patients were also detected. In 3 cases, 2 of them were other types of chromosomal aberrations. Conclusion: Ph1 chromosome is an independent cytogenetic marker of CML. Chromosome aberrations other than double Ph1 and standard Ph1 may indicate the transition to blast crisis, but mutation of Ph1 chromosome does not accelerate the transition from chronic phase to blast phase.