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感染性休克是临床上常见的危重病症,诊治困难,死亡率高。在临床上,对感染性休克病人作精细的对照研究十分困难,有时甚至不可能。这是因为:1)不同的原发病和不同的病原微生物对休克进程可有不同的影响;2)临床上不允许为研究目的而停止一切治疗措施,因此对感染性休克自然过程的研究几乎不可能;3)临床上接受研究者均已处于休克状态,许多指标的测定不可能作正常状态和休克后状态的自体对照;4)在研究一项新治疗措施时往往不能停止原有习用的措施,因而对新措施难以作出
Septic shock is a clinically common critical illness, diagnosis and treatment difficulties, high mortality. Clinically, it is very difficult, sometimes impossible, to make a detailed, controlled study of patients with septic shock. This is because: 1) different primary pathogens and different pathogenic microorganisms can have different effects on the process of shock; 2) clinically disallowed for the purpose of the study to stop all treatment, so the natural process of septic shock almost Impossible; 3) Clinically accepted by the investigators are in a state of shock, the determination of many indicators can not be normal and post-shock state of self-control; 4) In the study of a new treatment often can not stop the conventional Measures, and thus difficult to make new measures