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绪言很早以前,人们就注意到了锶对骨骼的影响。1874年K(?)rnig氏最早提出了锶可以置换骨中之钙。1908年Stoeltzner氏首次报告了关于锶性佝偻病的实验材料。该氏给小狗饲以少钙食物同时投与燐酸锶,结果动物长骨骨端部及肋骨骨软骨境界部肥大,骨质柔软,骺板软骨增厚,干骺端有致密的骨小樑增生,但钙鹽沉着很少。这些改变和佝偻病很类似。以后陸续有很多关于锶的研究,由于实验方法和条件不同,有些得出的是类似佝偻病的改变,有些得出的是有坚靱致密的骨质增生,即所谓锶性骨硬化症。
Long before the introduction, people noticed the impact of strontium on the skeleton. 1874 K (?) Rnig’s first proposed strontium can replace bone calcium. 1908 Stoeltzner’s first report on experimental materials on strontium rickets. The dog fed with calcium-less food at the same time cast strontium acid, the results of the long bones of the animal bone and cartilage border hypertrophy, soft bone, epiphyseal plate cartilage thickening, metaphyseal dense trabecular hyperplasia, However, calcium salt sedation. These changes are very similar to rickets. Since then there are many studies on strontium, due to different experimental methods and conditions, some are similar to the change of rickets, and some come with a firm and dense bone hyperplasia, the so-called strontium osteosclerosis.