本文通过用T细胞膜表面Fc受体方法对34例不同病期的单纯性肾病患儿进行了57例次的周围血Tγ和Tμ细胞的测定,并对其中8例进行了动态观察,结果发现肾病活动期存在着明显的T细胞亚群紊乱,主要表现为Tγ细胞和Tγ/Tμ值显著升高。这种紊乱与肾病的发病有一定联系。通过治疗前、中、后Tγ和Tμ细胞的变化认为强的松、环磷酰胺对Tγ细胞有选择性抑制作用,而对Tμ细胞无影响。 In this paper, T cell surface Fc receptor in 34 cases of simple nephropathy at different stages of 57 cases of peripheral blood T gamma and Tμ cells were measured and 8 cases were observed in the dynamic and found that kidney disease There was a significant disturbance of T cell subsets during the active phase, which was mainly manifested as a marked increase of Tγ cells and Tγ / Tμ values. This disorder and the incidence of kidney disease have a certain link. Prednisone and cyclophosphamide showed selective inhibition on Tγ cells through Tγ and Tμ cell changes before, during and after treatment, but had no effect on Tμ cells.