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目的:探讨儿童细菌性脑膜炎以及病毒性脑膜炎应用效果。方法:选取本院收治的儿童脑膜炎患者62例为研究对象,根据患儿感染类型将其分为细菌性脑膜炎30例以及病毒性脑膜炎32例,同时选取50例正常患儿为对照组,采用免疫荧光法检测两组患者血清中降钙素原(PCT)在儿童细菌性及病毒系那个脑膜炎中变化情况。结果:病毒性脑膜膜炎组PCT的值为(0.21±0.14)ng/ml,与正常对照组差异无显著性(P>0.05);细菌性脑膜膜炎组PCT的值为(5.25±3.01)ng/ml,升高明显,与正常对照组和病毒性脑膜炎组比较差异有显著性(P<0.05)。结论:血清PCT对病毒性脑膜炎和细菌性脑膜炎的鉴别诊断有重要的参考价值。
Objective: To investigate the application of bacterial meningitis and viral meningitis in children. Methods: Totally 62 children with meningitis admitted to our hospital were enrolled in this study. According to their infection types, 30 cases of bacterial meningitis and 32 cases of viral meningitis were divided into two groups. At the same time, 50 normal children were selected as the control group Immunofluorescence was used to detect the changes of serum procalcitonin (PCT) in children with bacterial and viral meningitis. Results: The PCT value of viral meningitis group was (0.21 ± 0.14) ng / ml, with no significant difference from the normal control group (P> 0.05). The PCT value of bacterial meningitis group was (5.25 ± 3.01) ng / ml, increased significantly, compared with the normal control group and viral meningitis group was significantly different (P <0.05). Conclusion: Serum PCT has important reference value in the differential diagnosis of viral meningitis and bacterial meningitis.