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目的:观察缺氧预适应对小鼠常压耐缺氧存活时间的影响。方法:对小鼠先施加短暂的缺氧至喘息,30分钟后进行致死性缺氧,观察其存活时间并与对照组比较。结果:缺氧预适应组小鼠的存活时间为24.0±3.30分,而空白对照小鼠的存活时间为19.28±3.92分,两者具有显著差异(P<0.01)。结论:缺氧预适应能延长小鼠的耐缺氧存活时间。
Objective: To observe the effect of hypoxic preconditioning on hypoxia-tolerance survival time in mice. Methods: Short-term hypoxia was applied to the mice to wheeze. After 30 minutes, lethal hypoxia was observed. The survival time was observed and compared with that of the control group. Results: The survival time of hypoxic preconditioning mice was 24.0 ± 3.30, while that of blank control mice was 19.28 ± 3.92, with significant difference (P <0.01) . Conclusion: Hypoxic preconditioning prolongs hypoxia-tolerant survival in mice.