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为了研究在患糖尿病时,口服葡萄糖对胰多肽(PP)分泌的影响,作者对81例经葡萄糖耐量证实的成年发病型糖尿病患者(26～74岁)及128例体重正常、无内分泌及肠功能异常的正常人(20～82岁),进行空腹及口服50克葡萄糖后血浆PP和胰岛素的放射免疫测定。结果发现,正常人血浆PP的含量随年龄的增加而升高;服糖后5分钟,血浆PP即由85±10pg/ml(空腹水平)升高到194±58pg/ml;15分钟含量最高(236±65pg/ml)。 在糖尿病患者,空腹血浆PP的含量也随年龄
To investigate the effect of oral glucose on the secretion of pancreatic polypeptide (PP) in patients with diabetes mellitus, 81 patients with adult-onset diabetes mellitus (26-74 years old) with glucose tolerance and 128 normal, non-endocrine and bowel functions Abnormal normal (20 to 82 years old), fasting and oral administration of 50 g glucose plasma PP and insulin radioimmunoassay. The results showed that the content of plasma PP increased with the increase of age in normal subjects. Plasma PP increased from 85 ± 10 pg / ml (fasting level) to 194 ± 58 pg / ml at 5 minutes after oral administration of sugar and reached the peak at 15 minutes 236 ± 65 pg / ml). In diabetic patients, the content of fasting plasma PP also varies with age