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引起新生儿胆汁淤积(迁延性高结合胆红素血症)的病因复杂,诊断困难,本文旨在讨论有关发病和诊疗方面的一些新进展。促使新生儿发生胆汁淤积的因素新生儿易有胆汁淤积(生理性)与以下因素有关;肝细胞分泌功能不成熟;某些能引起肝功能障碍的遗传代谢病可首先在新生儿期出现症状;不成熟的肝细胞易受病毒和毒素的损
The etiology of neonatal cholestasis (persistent hyperbilirubinemia) is complicated and difficult to diagnose. This article aims to discuss some new advances in the pathogenesis and diagnosis of this condition. Factors that promote cholestasis in newborns Neonatal easy to have cholestasis (physiological) and the following factors; hepatocyte secretory function is immature; some of the genetic metabolic diseases can cause liver dysfunction may first appear in the neonatal period symptoms; Immature liver cells are vulnerable to viruses and toxins