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目的 评价同步间歇指令通气—压力支持水平 (SIMV-PS)通气方式对老年慢性阻塞性肺病 (COPD)合并肺性脑病的疗效及在脱机中的应用。 方法 采用SIMV -PS方式 ,观察通气前后及脱机前后pH、PaCO2 、和PaO2的变化。 结果 通气后平均1.6±0.2h意识转清 ,pH和PaO2 显著升高 (均P<0.01) ,PaCO2 显著下降 (P<0.01) ;而脱机前后 pH、PaCO2 和PaO2 无显著性差异 (均P>0.05)。结论 采用SIMV -PS通气方式能有效地改善通气 ,并可顺利脱机而防止患者对呼吸机的依赖 ,是目前救治老年COPD合并肺性脑病较理想的通气及脱机方式。
Objective To evaluate the efficacy of synchronized intermittent mandatory ventilation-pressure support level (SIMV-PS) ventilation in elderly patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary encephalopathy and its application in off-line. Methods The changes of pH, PaCO2, and PaO2 before and after ventilation and before and after ventilation were observed by SIMV-PS. Results After ventilated for an average of 1.6 ± 0.2h, the values of PaCO2 and PaCO2 were significantly decreased (P <0.01) > 0.05). Conclusion SIMV-PS ventilation can effectively improve the ventilation, and can be successfully off-line to prevent the patient’s dependence on the ventilator, is currently the ideal treatment of elderly COPD with pulmonary encephalopathy ventilation and off-line way.