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腺苷是一种具有强大电生理作用的内源性嘌呤核苷 ,经磷酸化后参与心肌能量代谢抑制心肌收缩力及心率 ,腺苷通过作用于腺苷受体 (Ａ1)、激活外向钾电流 ,延长动作电位和静息膜电位的时间使窦性心律减慢以及房室传导阻滞。我们观察了 5 6例健康受试者 ,研究其对正常人房室结的影
Adenosine is a kind of endogenous purine nucleoside which has a strong electrophysiological effect. After being phosphorylated, adenosine participates in myocardial energy metabolism and inhibits myocardial contractility and heart rate. Adenosine activates outward potassium current by acting on adenosine receptor (A1) , Extend the action potential and resting membrane potential of the time to slow sinus rhythm and atrioventricular block. We observed 56 healthy subjects and studied their effects on normal atrioventricular node