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【目的】探讨通过鼻负压置换术治疗儿童支气管哮喘合并变应性鼻炎的临床疗效。【方法】将84例支气管哮喘合并变应性鼻炎的儿童随机分为观察组130例和对照组128例，观察组同时给予经口鼻吸入糖皮质激素并结合鼻负压置换术，对照组只给予经口鼻吸入糖皮质激素，治疗6个月，判定两组临床疗效。【结果】观察组哮喘缓解总有效率为92．31％，鼻炎缓解总有效率为93．85％；而对照组哮喘缓解总有效率为77．34％，鼻炎缓解总有效率为62．5％，两组总有效率比较差异具有统计学意义（ P ＜0．05）。【结论】鼻负压置换术治疗儿童支气管哮喘合并变应性鼻炎，可有效控制症状，缩短发病时间，延长稳定过程，提高患儿生活质量；且操作简便安全，副作用小，费用低，疗效显著，基本无创伤，不良反应少，易为患儿及操作者所接受，值得临床推广。“,”Objective]To explore the clinical efficacies of nasal negative pressure replacement plus inhaled corticoste‐roids in children with bronchial asthma complicated with allergic rhinitis .[Methods]A total of 258 children with bronchial asthma complicated with allergic rhinitis were recruited from our center from October 2012 to September 2014 and ran‐domly divided into observation ( n=130) and control ( n=128) groups .The observation group received corticosteroids inhalation by mouth and nose plus nasal negative pressure replacement while the control group had only corticosteroids in‐halation by mouth and nose .And the clinical efficacies were assessed after 6‐month treatment .[Results]In observation and control groups ,the overall asthma relief rates were 92 .31% versus 77 .34% while the overall rhinitis relief rates 93 .85%versus 62 .5% respectively .There were differences of statistical significance ( P <0 .05) .[Conclusion]Nasal negative pressure replacement plus inhaled corticosteroids can effectively control the symptoms ,shorten the course of disease ,pro‐long the period of stability and improve the life quality of children with bronchial asthma complicated with allergic rhinitis . It may be readily accepted by children because of simple and safe procedures .Furthermore ,it is mini‐invasive ,affordable and has few side effects so that wider clinical applications are desired .