本实验利用从南蛇藤(Celastrus Orbiculatus Thumb)的根分离和提取的卫茅醇,在常压下合成抗癌剂二澳卫茅醇。其合成最佳温度为90℃(±1℃);适宜加热时间为9小时;氢溴酸浓度应不低于69—70％;重结晶溶剂沸点不能太高,加热时间不能太长。通过其乙酰衍生物,元素分析,质谱和核磁共振谱等测定,确认为二溴卫茅醇。 In this experiment, we used methanol from the root of Celastrus Orbiculatus Thumb isolated and extracted at room temperature, the anti-cancer agent two mandeitol. The synthesis of the best temperature of 90 ℃ (± 1 ℃); suitable heating time of 9 hours; the concentration of hydrobromic acid should not be less than 69-70%; recrystallization solvent boiling point can not be too high, the heating time can not be too long. It was confirmed to be dibromitolitol by the measurement of its acetyl derivative, elemental analysis, mass spectrum and nuclear magnetic resonance spectrum.