目的:探讨复方苦参注射液在晚期非小细胞肺癌患者治疗中的应用效果及对患者生存质量的影响。方法:选择该院2011年6月—2012年7月收治的晚期非小细胞肺癌患者96例,按1∶1比例分入观察组或对照组,对照组给予吉西他滨+顺铂进行治疗,观察组在对照组基础上加用复方苦参注射液治疗,连续治疗2个疗程后评价疗效及生存质量的差异。结果:对照组患者总有效率为29.17%,疾病控制率66.67%;观察组总有效率为43.75%,疾病控制率85.42%;经统计学分析,观察组患者总有效率及疾病控制率均明显优于对照组(P<0.05)。观察组不良反应发生率18.75%,明显低于对照组的37.5%,差异具有统计学意义(P<0.05)。结论:复方苦参注射液可明显提高非小细胞肺癌的治疗效果,改善患者生存质量,在非小细胞肺癌治疗中具有重要价值。 Objective: To investigate the effect of Compound Kushen Injection in the treatment of patients with advanced non-small cell lung cancer and its impact on the quality of life of patients. Methods: A total of 96 patients with advanced non-small cell lung cancer who were admitted to our hospital from June 2011 to July 2012 were enrolled in the observation group or control group according to the ratio of 1: 1. The control group was treated with gemcitabine plus cisplatin. The observation group On the basis of the control group, the compound Kushen injection was used. After two courses of continuous treatment, the curative effect and quality of life were evaluated. Results: In the control group, the total effective rate was 29.17% and the disease control rate was 66.67%. The total effective rate was 43.75% in the observation group and 85.42% in the control group. The statistical analysis showed that the total effective rate and disease control rate in the observation group were significantly Better than the control group (P <0.05). The incidence of adverse reactions in the observation group was 18.75%, which was significantly lower than that in the control group (37.5%), the difference was statistically significant (P <0.05). Conclusion: Compound Kushen injection can significantly improve the therapeutic effect of non-small cell lung cancer and improve the quality of life of patients, which is of great value in the treatment of non-small cell lung cancer.