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目的：提高对葡萄膜转移癌的认识以降低误诊率和及早发现原发肿瘤。方法：观察２６例葡萄膜转移癌的临床表现，分析好发部位、原发肿瘤和影像学检查特点，部分病例手术前行眼内穿刺细胞涂片检查，所有手术切除物送病理检查。结果：葡萄膜转移癌发生在脉络膜的占６９％；半数以上葡萄膜转移癌病例表现为视力下降、眼压升高、球结膜充血水肿、眼底肿物及非裂孔性视网膜脱离、角膜后沉着物和前房水混浊；原发肿瘤第一位是肺癌，其次是乳腺癌。结论：葡萄膜转移癌在临床可出现继发性青光眼、葡萄膜炎和非裂孔性视网膜脱离等病征；肺癌是首位原发肿瘤。
OBJECTIVE: To raise awareness of uveal metastases to reduce the rate of misdiagnosis and early detection of primary tumors. Methods: The clinical manifestations of 26 cases of uveal metastatic carcinoma were observed. The characteristics of the primary site, primary tumor and imaging were analyzed. In some cases, intraocular aspirate cell smear was performed before operation, and all the surgical resections were sent for pathological examination. Results: Uveal carcinoma accounted for 69% of the choroid; more than half of cases of uveal metastases showed decreased visual acuity, elevated intraocular pressure, bulbar conjunctival congestion and edema, ocular fundus and non-retinal detachment, posterior corneal deposition And aqueous humor in the anterior chamber; primary tumor is lung cancer, followed by breast cancer. CONCLUSIONS: Uveal metastases may present with secondary glaucoma, uveitis and non-retinal detachment in clinic. Lung cancer is the first primary tumor.