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耐甲氧西林金黄色葡萄球菌(Methicillin-resistant Staphylococcus aureus,MRSA)是影响新生儿重症监护病房(neonatal intensive care unit,NICU)内早产儿和新生儿感染的一个常见原因。新生儿特别容易定植及感染MRSA,这可能与其生理特性和某些潜在的危险因素相关。此外,MRSA菌株的特性及其传播模式的改变也对NICU易感MRSA产生了一定的影响。尽管积极的预防措施和先进的诊疗手段已用于临床的治疗,但是MRSA仍是导致NICU发病率和死亡率较高的显著因素。
Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of pre-and neonatal infections affecting the neonatal intensive care unit (NICU). Neonates are particularly susceptible to colonization and infection of MRSA, which may be related to their physiological characteristics and to some of the underlying risk factors. In addition, the characteristics of MRSA strains and their changes in transmission patterns also have some impact on NICU susceptible MRSA. Although aggressive precautions and advanced treatment have been used for clinical treatment, MRSA remains a significant factor contributing to the higher morbidity and mortality in NICU.