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目的对湖南省1997~2005年不合格粪便标本(不合格标本)急性弛缓性麻痹(AFP)病例进行临床诊断与分类分析,提高AFP病例分类的准确性,为保持无脊灰状态提供科学依据。方法采用AFP病例病毒学分类法,由湖南省AFP病例分类专家诊断小组每年定期审查所有AFP病例,重点对不合格标本AFP病例进行临床分析与诊断,根据流行病学、临床诊断、实验室病原学监测结果等资料综合分析,作出最终分类。结果湖南省1997~2005年共报告2031例AFP病例,均为脊髓灰质炎(脊灰)排除病例。其中不合格标本AFP病例270例,经诊断,主要病种为创伤性神经炎(26.7%)、格林巴利综合征(16.3%)、脑病(8.9%)、非脊灰肠道病毒感染(4.8%)等。结论AFP病例分类结果证明湖南省1997~2005年未发现脊灰野病毒病例,不合格标本AFP病例的临床诊断和最终分类结果为湖南省继续保持无脊灰状态提供重要依据。
Objective To investigate the clinical diagnosis and classification of acute flaccid paralysis (AFP) in unacceptable stool samples (unqualified samples) from 1997 to 2005 in Hunan Province, and to improve the accuracy of classification of AFP cases and provide a scientific basis for maintaining polio-free status. Methods AFP cases of virological classification, classification of cases by the AFP case experts in Hunan Province, a regular review of all AFP cases every year, focusing on the analysis of non-qualified specimens of AFP cases and diagnosis, according to epidemiology, clinical diagnosis, laboratory etiology Monitoring results and other comprehensive analysis of information to make the final classification. Results A total of 2031 AFP cases were reported from 1997 to 2005 in Hunan Province, all of which were polio (polio) cases. The 270 cases of AFP cases were failed, and the main diseases were traumatic neuritis (26.7%), Guillain-Barre syndrome (16.3%), encephalopathy (8.9%) and non-poliovirus %)Wait. Conclusions The classification results of AFP cases showed that no cases of poliovirus were found in Hunan Province from 1997 to 2005, and the clinical diagnosis and final classification results of AFP cases of non-conformities provided an important basis for the continuous maintenance of polio-free status in Hunan Province.