【摘 要】
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生长分化因子15(GDF15)广泛参与细胞凋亡、分化和增殖等病理生理过程,并在肿瘤的发生发展过程中起着双重作用,可为多种肿瘤疾病提供诊断和治疗价值。本文综述GDF15在卵巢肿瘤
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生长分化因子15(GDF15)广泛参与细胞凋亡、分化和增殖等病理生理过程,并在肿瘤的发生发展过程中起着双重作用,可为多种肿瘤疾病提供诊断和治疗价值。本文综述GDF15在卵巢肿瘤中的不同功能,探讨GDF15在卵巢肿瘤的诊断、预防和治疗中的不同价值。1人类GDF15的基本结构和特征人类GDF15基因位于染色体19p12.1-13.1,由3019个碱基对组成,有两个外显子和一个长约1820
GDF15 is widely involved in pathophysiological processes such as apoptosis, differentiation and proliferation, and plays a dual role in tumorigenesis and development. It can provide diagnostic and therapeutic value for a variety of oncological diseases. This article reviews the different functions of GDF15 in ovarian tumors and discusses the different values of GDF15 in the diagnosis, prevention and treatment of ovarian tumors. 1 Basic Structure and Characteristics of Human GDF15 The human GDF15 gene is located on chromosome 19p12.1-13.1 and consists of 3019 base pairs with two exons and a length of about 1820
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