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目的:探讨不同类型Ⅳ期肺癌(PT4)介入治疗的方法及其疗效。材料和方法:45例PT4中并肺内转移者15例,采用支气管动脉与肺动脉同时灌注化疗;并全肺叶不张者15例,采用支气管动脉与胸主动脉同时灌注化疗;并同侧胸积液者15例,采用支气管动脉加胸膜腔内灌注的双介入方法。结果:完全缓解7例,占15.6%;部分缓解13例,占28.9%;无变化20例,占44.4%;有进展5例,占11.1%。结论:双介入治疗PT_4的临床疗效与全身化疗相持平,甚至在某些方面优于全身化疗,这就为Ⅳ期肺癌的治疗另辟了一条途径并提供了科学依据。
Objective: To investigate the interventional treatment and efficacy of different types of stage IV lung cancer (PT4). Materials and Methods: Fifty-five patients with PT4 and intra-pulmonary metastasis included 15 patients who underwent bronchial arterial and pulmonary arterial infusion chemotherapy simultaneously; 15 patients with atelectasis were treated with simultaneous infusion of bronchial artery and thoracic aorta with chemotherapy; Fluids were used in 15 patients. Double-interventional methods using bronchial artery plus pleural perfusion were used. Results: Complete remission in 7 cases, accounting for 15.6%; partial remission in 13 cases, accounting for 28.9%; no change in 20 cases, accounting for 44.4%; progress in 5 cases, accounting for 11.1%. Conclusion: The clinical efficacy of dual interventional treatment of PT_4 is similar to that of systemic chemotherapy, and even better than systemic chemotherapy in some aspects. This provides another way for the treatment of stage IV lung cancer and provides a scientific basis.