论文部分内容阅读
方法 21例患者。其中霍奇金氏病(HD)12例,非霍奇金淋巴瘤(NHL)9例。用环己亚硝脲氮芥(CCNU)代替亚硝脲氯芥(BCNU)。在由4例患者组成的逐级增大剂量组中,CCNU最初用6mg/kg,按3mg/kg逐渐增加。预处理方案的组成是:CCNU(6～15mg/kg)移植前6天口服,鬼臼乙叉甙(VP_(16),60mg/kg)移植前4天静注,环磷酰胺(100mg/kg)移植前2天静注。移植当天
Methods 21 patients. There were 12 cases of Hodgkin’s disease (HD) and 9 cases of non-Hodgkin’s lymphoma (NHL). Instead of nitrouril chloride mustard (BCNU), chlorhexidine mustard (CCNU) was used. In a step-up dose group consisting of 4 patients, CCNU was initially increased by 6 mg/kg at 3 mg/kg. The composition of the conditioning regimen was: CCNU (6 to 15 mg/kg) was given orally 6 days before transplantation, Etoposide (VP_(16), 60 mg/kg) intravenously 4 days before transplantation, and cyclophosphamide (100 mg/kg) ) 2 days before transplantation, intravenous injection. On the day of transplantation