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目的观察羟考酮用于饱胃流产患者的镇痛效果。方法选择门诊行无痛人流的饱胃患者40例,ASAⅠ或Ⅱ级,年龄18~40岁,体重49~70kg,孕周5~10周。随机分为羟考酮组和对照组。羟考酮组患者入室后给予羟考酮0.1mg/kg静注,对照组患者静脉给予生理盐水0.1mg/kg。5min后手术医生消毒、铺巾,手术开始。记录患者入室后(T1)、牵拉宫颈时(T2)、手术结束后(T3)患者的VAS评分,记录患者术中呼吸循环情况和术后恶心呕吐等不良反应情况。结果羟考酮组患者在T2,T3时VAS评分明显低于对照组(P<0.05),并且无明显呼吸抑制及恶心呕吐发生。结论对于饱胃要求行流产手术的患者应用羟考酮在保证安全性同时可提供良好镇痛。
Objective To observe the analgesic effect of oxycodone in patients with full stomach abortion. Methods Outpatient painless patients with gastric pain in 40 patients, ASA Ⅰ or Ⅱ grade, aged 18 to 40 years old, weighing 49 to 70kg, gestational weeks 5 to 10 weeks. Randomly divided into oxycodone group and control group. Patients in the oxycodone group received oxycodone 0.1 mg / kg intravenously after admission, while patients in the control group received intravenous saline 0.1 mg / kg. Surgeons disinfected after 5min, shop towels, surgery began. The VAS scores were recorded after the patient entered the room (T1), the cervix was pulled (T2) and the end of the operation (T3). The adverse reactions such as respiration and circulation during operation and postoperative nausea and vomiting were recorded. Results The VAS score of oxycodone group was significantly lower than that of the control group at T2 and T3 (P <0.05), and no obvious respiratory depression and nausea and vomiting occurred. Conclusions Oxycodone is a good analgesic for patients with full stomach requiring abortion.