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５６例慢性浅表性胃炎患者，随机分成次枸橼酸铋（Ｄｅ－Ｎｏｌ）组和麦滋林－Ｓ组，治疗时间８周。结果Ｄｅ－Ｎｏｌ组胃窦炎症程度及活动度改善明显优于麦滋林－Ｓ组。重度炎症由４２．９％减为１０．３％，轻度炎症；由１７．０％增至４２．９％；１００％的炎症转为非活动性；其对幽门螺杆菌的清除率（８０％）明显优于麦滋林－Ｓ组（４１．７％）；对胃粘膜血流量的改善也非常明显，由２．３３±０．１０Ｖ增加到３．２１±０．１０Ｖ。这进一步肯定ＤｅＮｏｌ治疗慢性胃炎具有提高胃粘膜防御因子和削弱攻击因子双重作用。
Fifty-six patients with chronic superficial gastritis were randomly divided into De-Nol group and Mezalin-S group for 8 weeks. Results The degree and activity of gastric antral inflammation in De-Nol group was significantly better than that of Mezalin-S group. Severe inflammation was reduced from 42.9% to 10.3% with mild inflammation; from 17.0% to 42.9%; 100% of the inflammation turned inactive; its clearance of H. pylori (80 %) Was significantly better than that of Maketan-S group (41.7%). The improvement of gastric mucosal blood flow was also significant, from 2.33 ± 0.10V to 3.21 ± 0.10V. This further affirmation DeNol treatment of chronic gastritis has the dual role of increasing gastric mucosal defense factor and weakening attack factor.