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目的探讨弥漫浸润型胃癌的特点及诊治方法。方法对手术治疗的 2 3例弥漫浸润型胃癌的临床资料进行回顾性分析。结果弥漫浸润型胃癌症状隐匿 ,胃镜确诊率为 76.5 % ,胃肠钡餐确诊率为 94.4%。术中见腹水及腹膜转移率为 34 .8% ,浆膜侵透率为 87.0 %( 2 1/2 3)。本组根治切除率为 39.1% ,姑息切除率为 47.8% ,根治切除者 9例中 5例生存期超过 1年 ,另有 2例超过 3年。结论弥漫浸润型胃癌恶性度高 ,浸润范围大 ,预后差 ,胃肠钡餐检查比胃镜具有较高的确诊率 ,治疗上采取以手术治疗为主、辅以腹腔化疗等综合治疗以提高疗效
Objective To investigate the characteristics of diffuse infiltration of gastric cancer and diagnosis and treatment methods. Methods The clinical data of 23 cases of diffuse infiltrative gastric cancer treated by surgery were analyzed retrospectively. Results The symptoms of diffuse infiltration of gastric cancer were obscure. The diagnosis rate of gastroscopy was 76.5% and the diagnosis rate of gastrointestinal barium meal was 94.4%. Intraoperative ascites and peritoneal metastasis rate of 34.8%, serosa penetration rate of 87.0% (2 1/2 3). The group of radical resection rate was 39.1%, palliative resection rate was 47.8%, radical resection in 9 cases, 5 cases of survival over 1 year, and another 2 cases for more than 3 years. Conclusions Diffuse infiltrating type gastric cancer has high malignant degree, extensive infiltration range and poor prognosis. Gastrointestinal and barium meal examination has a higher diagnosis rate than gastroscope. Surgical treatment is the main method, combined with intraperitoneal chemotherapy to improve the curative effect.