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The crystal structure of the title compound(Z)-5-fluoro-3-(phenyl((5-(pyridin-3-ylmethyl)thiophen-2-yl)amino)methylene)indolin-2-one(C_(25)H_(18)FN_3OS,M_r=427.50)has been prepared and determined by single-crystal X-ray diffraction.The crystal is of orthorhombic,space group P2_12_12_1 with a=5.931(1),b=12.413(1),c=28.102(2)A,V=2090.4(3)A~3,Z=4,D_c=1.358 g/cm~3,F(000)=888,μ=0.186 mm~(-1),MoKa radiation(λ=0.71073),R=0.041 and wR=0.105 for 4567 observed reflections with I>2σ(I).X-ray diffraction analysis reveals that the indole and thiophene rings are not coplanar with a dihedral angle of 46.26(5)°.Intramolecular and intermolecular N-H…O hydrogen bonds together with C-H…πinterations can be observed in the lattice.
The crystal structure of the title compound (Z) -5-fluoro-3- (phenyl pyridin-3-ylmethyl) thiophen-2-yl) (18) FN_3OS, M_r = 427.50) has been prepared and determined by single-crystal X-ray diffraction. The crystal is of orthorhombic, space group P2_12_12_1 with a = 5.931 (1), b = 12.413 (2) A, V = 2090.4 (3) A ~ 3, Z = 4, D_c = 1.358 g / cm ~ 3, F (000) = 888 and μ = 0.186 mm ~ = 0.71073), R = 0.041 and wR = 0.105 for 4567 observed reflections with I> 2σ (I). X-ray diffraction analysis reveals that the indole and thiophene rings are not coplanar with a dihedral angle of 46.26 (5) °. Intramolecular and intermolecular NH ... O hydrogen bonds together with CH ... πinterations can be observed in the lattice.