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目的研究新辅助化疗结合保乳术治疗乳腺癌患者的临床效果。方法将医院2009年9月-2013年10月收治的乳腺癌患者80例随机分为观察组和对照组各40例,观察组给予新辅助化疗结合保乳术治疗,对照组采取根治术进行治疗。术后随访时间为3年,所有患者均行化疗,比较2组临床效果。结果观察组手术时间、住院时间均短于对照组,术中出血量、并发症的发生率均少于对照组,差异有统计学意义(P<0.05)。随访中,观察组癌症复发率、远处转移率与对照组比较,差异无统计学意义(P>0.05)。结论新辅助化疗结合保乳术治疗乳腺癌患者的临床效果较好,患者满意度高,且具有手术时间较短、术中出血量较少、并发症发生率较低、住院时间较短等优势,临床应用价值很高,值得进一步推广使用。
Objective To study the clinical effect of neoadjuvant chemotherapy combined with conservative surgery on breast cancer patients. Methods Eighty patients with breast cancer admitted from September 2009 to October 2013 in our hospital were randomly divided into observation group (40 cases) and control group (40 cases). The observation group received neoadjuvant chemotherapy combined with conservative surgery and the control group . The follow-up time was 3 years. All the patients underwent chemotherapy. The clinical effects of the two groups were compared. Results The operation time and hospital stay in the observation group were shorter than those in the control group. The incidences of bleeding and complications in the observation group were all less than those in the control group (P <0.05). Follow-up, the observation group cancer recurrence rate, distant metastasis rate compared with the control group, the difference was not statistically significant (P> 0.05). Conclusion Neoadjuvant chemotherapy and breast-conserving surgery in breast cancer patients with better clinical outcomes, patients with high satisfaction, and has a shorter operative time, less blood loss, lower complication rates, shorter hospital stay and other advantages , High clinical value, it is worth to further promote the use of.