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IgA肾病的免疫组织学改变是在肾小球基膜有IgA和补体C_3颗粒沉着。本病为免疫复合病之一。IgA抗体的产生与口腔粘膜局部的感染有关。病程中常由于扁桃体炎而反复出现肉眼血尿。故认为IgA肾病的发病、发展、加重均与上呼吸道感染有关。口腔扁桃体摘除是IgA肾病的治疗方法之一,它以除去感染源、改善免疫状态为目的。作者调查了IgA肾病扁桃体摘除和经治的2例,其结果术后蛋白尿、血尿改善者占25~100%,11个报告中有6个尿检改善占100%,同时血清IgA水平降低,也有肾功能改善的病例。由上所述,扁桃体摘除后,扁桃体炎及咽炎发病机
Immunohistological changes in IgA nephropathy are glomerular basement membrane with IgA and complement C_3 particle deposition. The disease is one of immune complex disease. The production of IgA antibodies is associated with local oral mucosal infections. Often due to tonsillitis in the course of recurring gross hematuria. Therefore, the incidence of IgA nephropathy, development, increase are associated with upper respiratory tract infection. Oral tonsillectomy is one of the treatment of IgA nephropathy, which aims to remove the source of infection, improve the immune status. The authors investigated two cases of tonsillectomy and treatment of IgA nephropathy. The results of postoperative proteinuria, hematuria accounted for 25 to 100%, 6 of 11 reports improved 100%, and serum IgA levels were also decreased Improved renal function cases. From the above, tonsillectomy, tonsillitis and pharyngitis pathogenesis