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目的探讨子宫肉瘤的诊断及治疗方法。方法回顾性分析1990年1月至2009年12月收治的23例子宫肉瘤患者的临床资料。结果临床表现为不规则阴道流血14例,下腹包块9例,无症状的子宫肌瘤病史4例,腹痛2例。19例行手术,4例子宫肌瘤术后诊断为子宫肉瘤,其中2例做二次手术,1例拒绝二次手术,1例待2年后复发二次手术。术后化学治疗11例,联合化疗方案2~4个疗程。2年存活率51%,5年存活率26%。结论子宫肉瘤临床表现缺乏特异性,主要为不规则阴道流血,怀疑子宫肉瘤或诊断为子宫肌瘤者,应立即做冰冻病理切片检查,以便及时发现子宫肉瘤,以决定手术范围,尽可能减少第二次手术。
Objective To investigate the diagnosis and treatment of uterine sarcoma. Methods The clinical data of 23 patients with uterine sarcoma admitted from January 1990 to December 2009 were analyzed retrospectively. Results The clinical manifestations of irregular vaginal bleeding in 14 cases, 9 cases of inferior abdomen mass, asymptomatic history of uterine fibroids in 4 cases, abdominal pain in 2 cases. Nineteen patients underwent surgery and 4 patients with uterine fibroids were diagnosed as uterine sarcomas. Two of them underwent secondary surgery, one refused secondary surgery and one had secondary recurrence 2 years later. Postoperative chemotherapy in 11 cases, combined with chemotherapy 2 to 4 courses. 2-year survival rate of 51%, 5-year survival rate of 26%. Conclusion: The clinical manifestations of uterine sarcoidosis is not specific, mainly irregular vaginal bleeding, suspected uterine sarcoma or diagnosis of uterine fibroids should be frozen pathological examination immediately in order to detect uterine sarcoma in time to determine the scope of the operation, as much as possible to reduce the number of Second surgery.