红霉素诱发胰腺炎在此前尚无报道。一位19岁女患者吞服红霉素20片,3小时后出现剧烈上腹部疼痛,散射到背部,伴恶心呕吐。患者否认饮酒,未经药物治疗。在急诊室洗胃,见一些红霉素片被洗出。上腹部有轻度触痛,面部见斑丘疹,血清淀粉酶1005u/L(正常:0～130u/L),血清脂酶1065u/L(正常:30～208u/L),血中酒精含量为0。腹部超声检查胰腺呈低回声反射,胆系未见异常,诊断为胰腺炎。经治疗,第4天腹痛消失,血清淀粉酶等恢复正常,出院。本例排除了其它药物或原因引起胰腺炎的可能性。关于红霉素引起胰腺炎的发病机 Erythromycin-induced pancreatitis has not been previously reported. A 19-year-old woman swallowed 20 tablets of erythromycin and developed severe upper abdominal pain 3 hours later, scattering to the back with nausea and vomiting. Patients denied drinking, without medication. Gastric lavage in the emergency room, see some erythromycin tablets were washed out. Mild tenderness on the abdomen, facial rash, serum amylase 1005u / L (normal: 0 ~ 130u / L), serum lipase 1065u / L (normal: 30 ~ 208u / L), blood alcohol content 0. Abdominal ultrasound examination of the pancreas showed hypoechoic reflex, gallbladder no abnormalities, diagnosis of pancreatitis. After treatment, abdominal pain disappeared on the 4th day, serum amylase returned to normal, discharged. This case rule out the possibility of other drugs or causes of pancreatitis. Erythromycin causes pancreatitis pathogenesis