癌症患者的血清中,一般认为存在免疫抑制因子。作者从实验中发现:IAP在胃癌患者的血清以及局部血清中均高,故考虑IAP是免疫抑制因子之一。 IAP为石田等所发现,系分子量约为59,000的酸性蛋白质,具有抑制PHA反应等免疫抑制作用,在动物实验中有促进肿瘤增殖作用。 In the serum of cancer patients, immunosuppressive factors are generally considered to be present. The authors found from the experiment that IAP is high in serum and local serum in patients with gastric cancer, so IAP is considered as one of the immunosuppressive factors. IAP was discovered by Ishida et al. As an acidic protein with a molecular weight of approximately 59,000, it has an immunosuppressive effect such as inhibition of PHA reaction and it has an effect of promoting tumor proliferation in animal experiments.