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将大鼠分为训练组和服药训练组 ,在两周内采用强度为 35 m/ s,坡度为 0的跑台训练 ,训练后进行速度为 38m/ s,坡度为 0的运动 35 min。服药组大鼠训练期间同时灌服中药。从测定红细胞内抗氧化酶活性Na+ ,K+ - ATP酶活性入手 ,探讨训练及大强度运动对大鼠红细胞氧自由基代谢状况发生变化的可能原因。研究表明 ,训练使大鼠红细胞内 SOD代谢情况发生适应性变化 ;大强度运动后 GPX活性的上升有助于细胞内 H2 O2 快速转化为 H2 O的能力 ;抗疲劳中药在一定程度上对训练中增加的氧自由基具有清除作用 ;训练鼠大强度运动后 Na+ ,K+ - ATP酶活性的升高有助于保持酶活性的稳定 ,抗疲劳中药在一定程度上改善红细胞膜转运 Na+ ,K+的能力。
The rats were divided into the training group and the medication training group. The treadmill with the intensity of 35 m / s and the slope of 0 was used within two weeks. After the training, the speed was 38 m / s and the slope was 0 for 35 minutes. The rats in the medication group were given traditional Chinese medicine while training. Starting from determining the activity of Na +, K + - ATPase in erythrocytes, we probed into the possible reasons for the changes of metabolism of oxygen free radical in rat erythrocytes after training and intensive exercise. The research shows that training can make adaptive changes of SOD metabolism in rat erythrocytes. The increase of GPX activity after intensive exercise contributes to the ability of intracellular H2O2 to be rapidly converted to H2 O. Anti-fatigue Chinese medicine to a certain extent, Increased oxygen free radicals have scavenging effect. Increasing Na +, K + -ATPase activity after training high-intensity training helps to maintain the stability of enzyme activity. Anti-fatigue medicine can improve the ability of erythrocyte membrane to transport Na +, K + to a certain extent .